Microsoft Defender for Endpoint is suddenly blocking Office, preventing users from opening documents. Moreover, a number of executable files have also come under the hot hand. It turned out that the false positive detection of the Emotet malware was to blame.
Administrators of Windows computers complained about the problem. Judging by numerous reports, the bug appeared after the “Defender” was updated to version 1.353.1874.0. Thus, Microsoft Defender blocks the opening of files and issues a warning about suspicious activity related to Win32/PowEmotet.SB or Win32/PowEmotet.SC. Some administrators were unable to open Excel documents and cited the upgrade to version 1.353.1874.0 as the reason:
https://twitter.com/SydeEyeDotCom/status/1465800720821727235
While Microsoft hasn’t yet shared any info on what causes this situation, the most likely reason is that the company has increased the sensitivity for detecting Emotet-like behavior in updates released today, which makes Defender’s generic behavioral detection engine too sensitive prone to false positives.
Microsoft representatives have already responded to complaints from administrators and said that the corporation is working to fix the problem.

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